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Descriptor English: DNA Ligase ATP
Descriptor Spanish: ADN Ligasa (ATP)
Descriptor ADN-ligasa dependiente de ATP
Entry term(s) ADN Ligasas dependientes de ATP
ADN ligasa
ADN ligasa (ATP)
ADN ligasa II
ADN ligasa III
ADN ligasa IV
ADN ligasa dependiente de ATP
ADN-ligasa I
ADN-ligasa II
ADN-ligasa III
ADN-ligasa III alfa
ADN-ligasa IV
ADN-ligasas dependientes de ATP
ATP polidesoxirribonucleótido sintasa
ATP polidesoxirribonucleótido sintetasa
alfa-ADN ligasa III
polirribonucleótido-sintasa dependiente de ATP
proteína LIG III alfa
Scope note: Enzima celular dependiente de ATP que cataliza la replicación del ADN, la reparación y la recombinación mediante la formación de enlaces éster internucleotídicos entre residuos fosfato y desoxirribosa. Las células de los vertebrados codifican tres ADN-ligasas bien caracterizadas: ADN-ligasa I, III y IV, todas ellas relacionadas por su estructura y secuencia. Las ADN-ligasas requieren ATP o NAD. Sin embargo, las ADN-ligasas de arqueobacterias, virus y algunas eubacterias son dependientes de ATP.
Descriptor Portuguese: DNA Ligase Dependente de ATP
Descriptor French: DNA ligase ATP
Entry term(s): ATP, DNA Ligase
ATP, Polydeoxyribonucleotide Synthase
ATP-Dependent DNA Ligase
ATP-Dependent DNA Ligases
DNA Ligase I
DNA Ligase II
DNA Ligase III
DNA Ligase IIIalpha
DNA Ligase IV
DNA Ligases, ATP Dependent
DNA Ligases, ATP-Dependent
IIIalpha, DNA Ligase
LIGIIIalpha Protein
Ligase ATP, DNA
Ligase I, DNA
Ligase II, DNA
Ligase III, DNA
Ligase IIIalpha, DNA
Ligase IV, DNA
Ligases, ATP-Dependent DNA
Polydeoxyribonucleotide Synthase ATP
Synthase ATP, Polydeoxyribonucleotide
Tree number(s): D08.811.074.500.500
D08.811.464.754.600.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072481
Scope note: ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 6.5.1.1
Public MeSH Note: 2018; DNA LIGASE (ATP) was indexed under DNA LIGASES 1986-2016; DNA LIGASE IIIALPHA was indexed under DNA LIGASES 1991-2017
History Note: 2018 (1986)
DeCS ID: 56464
Unique ID: D000072481
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/06/29
DNA Ligase ATP - Preferred
Concept UI M000619283
Scope note ATP-dependent cellular enzyme which catalyzes DNA replication, repair and recombination through formation of internucleotide ester bonds between phosphate and deoxyribose moieties. Vertebrate cells encode three well-characterized DNA ligases, DNA ligase I, III and IV, all of which are related in structure and sequence. DNA ligases either require ATP or NAD. However, archaebacterial, viral, and some eubacterial DNA ligases are ATP-dependent.
Preferred term DNA Ligase ATP
Entry term(s) ATP, DNA Ligase
ATP, Polydeoxyribonucleotide Synthase
ATP-Dependent DNA Ligase
ATP-Dependent DNA Ligases
DNA Ligases, ATP Dependent
DNA Ligases, ATP-Dependent
Ligase ATP, DNA
Ligases, ATP-Dependent DNA
Polydeoxyribonucleotide Synthase ATP
Synthase ATP, Polydeoxyribonucleotide
DNA Ligase I - Narrower
Concept UI M0472159
Preferred term DNA Ligase I
Entry term(s) Ligase I, DNA
DNA Ligase IIIalpha - Narrower
Concept UI M0480519
Preferred term DNA Ligase IIIalpha
Entry term(s) IIIalpha, DNA Ligase
LIGIIIalpha Protein
Ligase IIIalpha, DNA
DNA Ligase IV - Narrower
Concept UI M0472161
Preferred term DNA Ligase IV
Entry term(s) Ligase IV, DNA
DNA Ligase III - Narrower
Concept UI M000618783
Preferred term DNA Ligase III
Entry term(s) DNA Ligase II
Ligase II, DNA
Ligase III, DNA



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